Bioinorganic chemistry

1)  Complex chemistry. Nomenclature of complex compounds The structure and types of metal complexes. The formation and stability of complexes. Binding theory of complex compounds: crystal space and molecular path theory. Magnetic properties of transition metal ions. Pearson's acid-base theory. The effect of complex formation on the redox properties of metal ion                     2 hours

2)  Important elements for living organisms and their grouping. Biochemical evolution of vital elements. The role of changing the environment in life. Development of catalysis. Changing the role of metal ions and their complexes during evolution. Toxic effect. Environmental pollution and enrichment of metals. The damaging effects of metals.                                                                                                 2 hours

3)The role of alkali metals in biological systems. Alkali metal complexes. Cell transport processes. The Na-K balance, the mechanism of the ion pump. The biological effect of lithium and rubidium.

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4)The role of alkaline earth metals in biological systems. The role of magnesium, calcium, strontium, barium, radium.                                                                                                                      2 hours

5)Boron and living organisms. Aluminum, its introduction into the human body, its pathophysiological effects, its possible role in Alzheimer's disease.                                                                     2 hours

6)The biological role of silicon in plants in animals and in the human body. Inorganic silicon compounds in medicine. Silicon-dioxide particles and silicic-acid derivatives. Application of silicone polymers in medicine. Prostheses, implants, therapeutic excipients, transdermal systems.                                     2 hours

7)Bioactive Organic Silicon Compounds. Silylated derivatives of known organic pharmacones. Bioactive silicon compounds without carbon analogues, silapharmacones. Silicon containing pesticides.   2 hours

8)V / 1. group elements. Biological and chemical binding of nitrogen. Circumference of nitrogen. The role of phosphorus compounds in cell energy production processes. The effects of arsenic and its compounds.

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9)Elements of VI / 1 group. The biological role of oxygen. Reactive derivatives derived from oxygen and their elimination. The mechanism of oxygen activation. Binding and transport of oxygen. The physiological role of sulfur hydrogen. The bio-inorganic role of selenium.                                       2 hours

10)The biological significance of halogens. The biological role of fluorine, chlorine, bromine and iodine.                                                                                                                                             2 hours

11)The role of d-elements in biological processes. The formation of complexes. Toxic effects. Bio-inorganic chemistry of vanadium, chromium, molybdenum, manganese.                                                        2 hours

12)Bio-inorganic chemistry of iron, cobalt and nickel.                                                                           2 hours

13)Biological use of platinum and its compounds. The bio-inorganic chemistry of the copper group elements. The biologic effect of copper, silver and gold.                                                                 2 hours

14)

The biological significance of the zinc group's elements. The biological role of zinc. Zinc containing enzymes in various biochemical processes.  Bio-inorganic chemistry of cadmium and mercury.